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Molecular Neurosurgery with Targeted Toxins - DOUGLAS A. LAPPI - RONALD G. WILEY

Molecular Neurosurgery with Targeted Toxins

Publisher title : Molecular Neurosurgery with Targeted Toxins

DOUGLAS A. LAPPI
RONALD G. WILEY

 
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Pioneers and leading researchers explain the theory and techniques of using targeted toxins experimentally. The highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals is treated in detail to give a potential user the knowledge to comfortably use the techniques involved. The uses of important new lesioning agents such as anti-DBH-saporin immunotoxin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin that can produce narcoleptic animals, and other saporin conjugates, such as neuropeptide-saporin conjugates for pain research and cholera toxin B chain-saporin to produce a model of CNS demyelination are explained by experts in the field.

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Price: $161.38
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Author:  DOUGLAS A. LAPPI
RONALD G. WILEY
Title: Molecular Neurosurgery with Targeted Toxins
Release date: October 2007
Editor: LIVRES NUMÉRIQUES DIVERS
Subject: NUL DIVERS
ISBN: 9781592598960 (159259896X)
Renaud-Bray Reference: 2155132
Item nb: 2155132
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Format: PDF
Availability : Canada, other authorized countries.
Digital Rights Management : Adobe DRM
Numeric warehouse : NUMILOG
Number of authorized devices: 3
Number of copy-and-pastes: 0
Print: 0

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Molecular Neurosurgery with Targeted Toxins , LAPPI , DOUGLAS A.*WILEY , RONALD G.
© LIVRES NUMÉRIQUES DIVERS 2007
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