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Innovations for Next-Generation Antibody-Drug Conjugates
Publisher title : Innovations for Next-Generation Antibody-Drug Conjugates
MARC DAMELIN
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Summary
Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.
Details
Price:
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$156.74
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Category:
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Author:
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MARC DAMELIN
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Title:
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Innovations for Next-Generation Antibody-Drug Conjugates
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Release date:
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May 2018
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Editor:
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LIVRES NUMÉRIQUES DIVERS
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Subject:
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NUL DIVERS
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ISBN:
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9783319781549 (3319781545)
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Renaud-Bray Reference:
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2555486
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Item nb:
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2555486
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Digital rights
Format:
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PDF
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Availability :
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Canada,
other authorized countries.
Innovations for Next-Generation Antibody-Drug Conjugates
By
DAMELIN , MARC
ANDORRE
ÉMIRATS ARABES UNIS
ARMÉNIE
ANTARCTIQUE
ARGENTINE
SAMOA AMÉRICAINES
AUTRICHE
AUSTRALIE
BOSNIE-HERZÉGOVINE
BARBADE
BELGIQUE
BULGARIE
BAHREÏN
BURUNDI
BERMUDES
BRUNÉI DARUSSALAM
BOLIVIE
BRÉSIL
BAHAMAS
BOUVET, ÎLE
BELIZE
Canada
SUISSE
COOK, ÎLES
CHILI
CHINE
COLOMBIE
COSTA RICA
CUBA
CHRISTMAS, ÎLE
CHYPRE
TCHÈQUE, RÉPUBLIQUE
ALLEMAGNE
DANEMARK
DOMINIQUE
DOMINICAINE, RÉPUBLIQUE
ALGÉRIE
ÉQUATEUR
ESTONIE
ÉGYPTE
ESPAGNE
FINLANDE
FALKLAND, ÎLES (MALVINAS)
FÉROÉ, ÎLES
FRANCE
GRENADE
GUYANE FRANÇAISE
GIBRALTAR
GROENLAND
GUADELOUPE
GRÈCE
GUATEMALA
GUYANA
HONG-KONG
HEARD, ÎLE ET MCDONALD, ÎLES
HONDURAS
CROATIE
HAÏTI
HONGRIE
INDONÉSIE
IRLANDE
ISRAËL
INDE
OCÉAN INDIEN, TERRITOIRE BRITANNIQUE DE
IRAN, RÉPUBLIQUE ISLAMIQUE D'
ISLANDE
ITALIE
JAMAÏQUE
JAPON
KENYA
KIRGHIZISTAN
CAMBODGE
COMORES
SAINT-KITTS-ET-NEVIS
CORÉE, RÉPUBLIQUE DE
CAÏMANES, ÎLES
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Digital Rights Management :
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Adobe DRM
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Numeric warehouse :
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NUMILOG
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Number of authorized devices:
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3
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Number of copy-and-pastes:
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0
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Print:
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0
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Innovations for Next-Generation Antibody-Drug Conjugates
,
DAMELIN , MARC
©
LIVRES NUMÉRIQUES DIVERS
2018
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