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Tumors of the Central Nervous System, Volume 5 - M.A. HAYAT

Tumors of the Central Nervous System, Volume 5

Titre de l'éditeur : Tumors of the Central Nervous System, Volume 5

M.A. HAYAT

 
275,82 $
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EN SAVOIR PLUS Résumé

The most recent developments in diagnostic and therapeutic aspects of Gliomas (glioblastoma) in the brain are presented.  The importance of personalized medicine and clinical validation for targeted therapy are discussed. The identification of various types of biomarkers (determined by molecular genetics) is included, along with their advantages and limitations as markers in tumor detection and diagnosis. The identification and validation of brain cancer (glioblastoma) genes are discussed. The role of cancer stem cells in the initiation and persistence of malignant gliomas is explained; response of glioblastoma cancer stem cells to various growth factors, such as epidermal growth factor receptor kinase inhibitor, is explained. The use of surgical resection, chemotherapy (e.g., temozolomide), immunotherapy, and radiation therapy for glioblastoma patients is included. Biological impediments for chemotherapy and radiotherapy for malignant glioblastoma are pointed out. Standard (established) as well as newer imaging modalities (proton magnetic resonance spectroscopy) are discussed. Also included are proton magnetic resonance spectroscopy in intracranial gliomas, and the use of proton magnetic spectroscopic imaging in determining the infiltration zone in gliomas. The role of molecular signaling in the CNS cancer development is explained, including cell death signaling in glioblastoma multiforme.

The most recent developments in diagnostic and therapeutic aspects of Gliomas (glioblastoma) in the brain are presented.  The importance of personalized medicine and clinical validation for targeted therapy are discussed. The identification of various types of biomarkers (determined by molecular genetics) is included, along with their advantages and limitations as markers in tumor detection and diagnosis. The identification and validation of brain cancer (glioblastoma) genes are discussed. The role of cancer stem cells in the initiation and persistence of malignant gliomas is explained; response of glioblastoma cancer stem cells to various growth factors, such as epidermal growth factor receptor kinase inhibitor, is explained. The use of surgical resection, chemotherapy (e.g., temozolomide), immunotherapy, and radiation therapy for glioblastoma patients is included. Biological impediments for chemotherapy and radiotherapy for malignant glioblastoma are pointed out. Standard (established) as well as newer imaging modalities (proton magnetic resonance spectroscopy) are discussed. Also included are proton magnetic resonance spectroscopy in intracranial gliomas, and the use of proton magnetic spectroscopic imaging in determining the infiltration zone in gliomas. The role of molecular signaling in the CNS cancer development is explained, including cell death signaling in glioblastoma multiforme.


Détails
Prix : 275,82 $
Catégorie :
Auteur :  M.A. HAYAT
Titre : Tumors of the Central Nervous System, Volume 5
Date de parution : septembre 2011
Éditeur : LIVRES NUMÉRIQUES DIVERS
Sujet : NUL DIVERS
ISBN : 9789400720190 (940072019X)
Référence Renaud-Bray : 3061031
No de produit : 3061031
Droits numériques
Format : EPUB
Disponibilité : Non disponible au Canada, consultez la liste des pays autorisés.
Gestion des droits numériques : Adobe DRM
Entrepôt numérique : NUMILOG
Nombre d'appareils autorisés : 3
Nombre de copier/coller : 0
Impression : 0

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Tumors of the Central Nervous System, Volume 5 , HAYAT , M.A.
© LIVRES NUMÉRIQUES DIVERS 2011