LIVRES JEUNESSEBÉBÉJEUX, JOUETSPAPETERIECADEAUXDIVERTISSEMENT


Message Important
Le site sera temporairement en maintenance, pour une mise à jour. Ceci afin de mieux vous servir.
Heure de maintenance prévue : 10:30 pm

Important message
The site will be busy updating the store for you and will be back shortly.
Scheduled maintenance : 10:30 pm
LIVRES NUMÉRIQUES
Next-Generation Therapies and Technologies for Immune-Mediated Inflammatory Diseases - PAOLA MINA-OSORIO

Next-Generation Therapies and Technologies for Immune-Mediated Inflammatory Diseases

Titre de l'éditeur : Next-Generation Therapies and Technologies for Immune-Mediated I

PAOLA MINA-OSORIO

 
205,39 $
Feuilleter Feuilleter
Ajouter à ma liste de souhaits
EN SAVOIR PLUS Résumé

As our understanding of immune mediated chronic inflammatory diseases (IMIDs) grows, it becomes more and more clear that these conditions result from the convergence of a multitude of pathogenic mechanisms whose relative individual contribution is different in different patient subsets.

Promising new technologies have been conceived that address the hypotheses that targeting multiple pathways simultaneously, selectively delivering therapeutics to areas of inflammation and/or resetting the immune system, could take efficacy to new levels. However, we have long waited for the arrival of some of these technologies to the bedside, or even far enough in the drug development process in spite of the initial enthusiasm. Some of the examples covered in this book include bispecific antibodies and genomic medicines, microparticles and targeted delivery of drugs to inflamed vasculature.

Most published reviews and book chapters on novel therapies for inflammatory diseases describe positive attributes of molecules or technologies under investigation and the rationale for developing them into therapeutics. The originality and potential value of this book is not in the description of these targets or technologies from the point of view of their structure or mechanism of action exclusively, but rather, in making an effort to critically address the question of what is needed to move these technologies into the clinic. Has the technology not made it past the preclinical stage and why? Has it already been tested in humans and failed? What are the potential reasons behind those failures? What do experts in each field believe can be done better to increase the probabilities of success?

In addition, the authors address the competitive landscape and summarize clinical studies that have failed in the respective area. They talk about the patient populations that would be required for the successful conduction of a clinical trial to test certain molecules, and they proactively share their views regarding both the potential and the drawbacks of targets or methodologies.



Détails
Prix : 205,39 $
Catégorie :
Auteur :  PAOLA MINA-OSORIO
Titre : Next-Generation Therapies and Technologies for Immune-Mediated Inflammatory Diseases
Date de parution : décembre 2019
Éditeur : LIVRES NUMÉRIQUES DIVERS
Sujet : NUL DIVERS
ISBN : 9783319422527 (3319422529)
Référence Renaud-Bray : 2178962
No de produit : 2178962
Droits numériques
Format : EPUB
Disponibilité : Canada, consultez la liste des pays autorisés.
Gestion des droits numériques : Adobe DRM
Entrepôt numérique : NUMILOG
Nombre d'appareils autorisés : 3
Nombre de copier/coller : 0
Impression : 0

SUGGESTIONS
Suggestions
Ce désir me point LEGENDRE, CLAIRE
13,99 $
Ce désir me point LEGENDRE, CLAIRE
13,99 $
Une vie sans peur et sans regret BOMBARDIER, DENISE
27,99 $
Next-Generation Therapies and Technologies for Immune-Mediated Inflammatory Diseases , MINA-OSORIO , PAOLA
© LIVRES NUMÉRIQUES DIVERS 2019